Adam Cohen: Visualizing cellular voltage

Adam Cohen: Visualizing cellular voltage

W hen ion concentrations differ on either side of a membrane, this produces a difference in electrical potential, or voltage, across the membrane. Neurons utilize this voltage to transmit information in the form of electrical signals. But might cell voltage also affect processes such as embryonic development or the behavior of yeast and other microbes? These questions cannot be answered using t...

Adam Cohen Thesis

Cellular Resolutions of Cohen-macaulay Monomial Quotient Rings

We investigate monomial labellings on cell complexes, giving a minimal cellular resolution of the ideal generated by these monomials, and such that the associated quotient ring is Cohen-Macaulay. We introduce a notion of such a labelling being maximal. There is only a finite number of maximal labellings for each cell complex, and we classify these for trees, partly for subdivisions of polygons,...

Visualizing cellular imaging data using PhenoPlot

Visualization is essential for data interpretation, hypothesis formulation and communication of results. However, there is a paucity of visualization methods for image-derived data sets generated by high-content analysis in which complex cellular phenotypes are described as high-dimensional vectors of features. Here we present a visualization tool, PhenoPlot, which represents quantitative high-...

ADAM 10 ( ADAM metallopeptidase domain 10 )